pulmonary responses to stachybotrys chartarum and its

pulmonary responses to stachybotrys chartarum and its

Can Stachybotrys be harmful to humans?Can Stachybotrys be harmful to humans?Stachybotrys is not a picky mold and can grow anywhere it finds enough moisture, including laundry rooms, poorly isolated basements, areas around leaky pipes and so on. Worryingly, some species of Stachybotrys produce mycotoxins which can be harmful to human beings if inhaled or ingested.Stachybotrys - Allergy, Health Symptoms & Treatment Mold pulmonary responses to stachybotrys chartarum and its(plate) Is Stachybotrys poisonous to humans?Is Stachybotrys poisonous to humans?However, Stachybotrys does produce mycotoxins that can have serious effects on the health of humans and animals as evidenced by many cases of poisoning in Russia and Eastern Europe [2]. It is far from harmless and more studies are needed to properly elucidate its association with human disease.Stachybotrys - Allergy, Health Symptoms & Treatment Mold pulmonary responses to stachybotrys chartarum and its(plate) Pulmonary Responses to Stachybotrys chartarum and Its pulmonary responses to stachybotrys chartarum and its

Apr 12, 2010Pulmonary Responses to Stachybotrys chartarum and Its Toxins Mouse Strain Affects Clearance and Macrophage Cytotoxicity

What does Stachybotrys mean?What does Stachybotrys mean?Stachybotrys is a genus of molds that can be found worldwide, in both indoor and outdoor settings. This article reviews this group of molds, their characteristics, the effects they can have on human health as well as sure ways of removing Stachybotrys mold.Stachybotrys - Allergy, Health Symptoms & Treatment Mold pulmonary responses to stachybotrys chartarum and its(plate) A Quantitative Risk Assessment for Stachybotrys

The inhalation exposure to Stachybotrys chartarum(SC) has been playing a critical role in public health domain due to its ability to produce toxins (trichothecene and other mycotoxins), that are implicated in the cases of acute idiopathic pulmonary hemorrhages (AIPH) in infants.(plate) Acute Inflammatory Responses to Stachybotrys chartarum in pulmonary responses to stachybotrys chartarum and its(steel) Jan 12, 2005Stachybotrys chartarum has been linked to building-related respiratory problems including pulmonary hemorrhage in infants. The macrocyclic trichothecenes produced by S. chartarum have been the primary focus of many investigations.

Author Joseph D. Brain, Nancy Long Sieber, Jamie H. Rosenblum LichtensteinPublish Year 2020Inhalation of Stachybotrys chartarum Evokes Pulmonary pulmonary responses to stachybotrys chartarum and its

Apr 20, 2011Abstract. Stachybotrys chartarum, a ubiquitous fungus in our environment, has been suspected of causing respiratory symptoms in humans, such as acute infant pulmonary hemorrhage and asthma.We previously established a mouse model in which repeated inhalation of Stachybotrys chartarum spores caused pulmonary hypertension. To further investigate the model, particularly in the pulmonary pulmonary responses to stachybotrys chartarum and its(plate) Author Joseph D. Brain, Nancy Long Sieber, Jamie H. Rosenblum LichtensteinPublish Year 2020Stachybotrys chartarum (or S. atra or S. alternans(steel) Apr 20, 2004Stachybotrys chartarum is a greenish-black mold in the fungal division Deuteromycota, a catch-all group for fungi for which a sexually reproducing stage is unknown. It produces asexual spores (conidia). The morphology and color of conidia and other (plate) Biological responses of Raw 264.7 macrophage exposed to pulmonary responses to stachybotrys chartarum and its(steel) Apr 21, 2016Pulmonary responses to Stachybotrys chartarum and its toxins mouse strain affects clearance and macrophage cytotoxicity. Lichtenstein JH, Molina RM, Donaghey TC, Amuzie CJ, Pestka JJ, Coull BA, Brain JD. Toxicol Sci, 116(1):113-121, 12 Apr 2010 Cited by 11 articles pulmonary responses to stachybotrys chartarum and its

Building-Associated Pulmonary Disease From Exposure pulmonary responses to stachybotrys chartarum and its

Moisture-damaged interior surfaces in both buildings were contaminated with S. chartarum, A. versicolor,and Penicillium species. Aspergillus species, especially A. versicolor, at concentrations of 10 1 to 10 4 /m 3 dominated the indoor air under normal operating conditions. Bulk samples also revealed large quantities of Stachybotrys.(plate) Cited by 14Publish Year 2011Author Masaru Nagayoshi, Yuji Tada, James West, Eri Ochiai, Akira Watanabe, Takahito Toyotome, Nobuhiro Tan pulmonary responses to stachybotrys chartarum and itsStachybotrys - Doctor Fungus(steel) The presence of IgE specific to Aspergillus spp., Cladosporium, and Stachybotrys chartarum in serum was found to be related to the sick building syndrome in another study . The second reason why Stachybotrys drew attention was its possible role in development of acute idiopathic pulmonary hemorrhage and hemosiderosis in infants. In the years pulmonary responses to stachybotrys chartarum and its(plate) Cited by 17Publish Year 2008Author Eri Ochiai, Katsuhiko Kamei, Akira Watanabe, Masaru Nagayoshi, Yuji Tada, Tetsutaro Nagaoka, Koichi pulmonary responses to stachybotrys chartarum and itspulmonary responses to stachybotrys (steel) stachybotrys chartarum levelsstachybotrys chartarum cdcstachybotrys chartarum igastachybotrys chartarum phylumstachybotrys mold symptomsSome results are removed in response to a notice of local law requirement. For more information, please see here.

Cited by 17Publish Year 2011Author Urvashi Bhan, Michael J. Newstead, Xianying Zeng, Megan N. Ballinger, Louis R. Standiford, Theodore pulmonary responses to stachybotrys chartarum and itsStachybotrys Chartarum - an overview ScienceDirect Topics

Although not commonly associated with bioaerosol exposure, a U.S. Centers for Disease Control and Prevention (CDC) report suggested that exposure to Stachybotrys chartarum was the cause of a cluster of acute pulmonary hemorrhage in 10 infants presenting at the Cleveland children's hospital in 199394 (CDC, 1994, 1997; Etzel et al., 1998).(plate) Cited by 20Publish Year 2006Author Jamie H. Rosenblum Lichtenstein, Ramon M. Molina, Thomas Clark Donaghey, Joseph David BrainBuilding-associated pulmonary disease from exposure to pulmonary responses to stachybotrys chartarum and its(steel) The authors present an outbreak of disease associated with exposure to Stachybotrys chartarum and Aspergillus species. A courthouse and two associated office buildings had generated discomfort among employees for two years since initial occupancy. Multiple interventions had been unsuccessful An init (plate) Cited by 20Publish Year 2006Author Jamie H. Rosenblum Lichtenstein, Ramon M. Molina, Thomas Clark Donaghey, Joseph David BrainStrain Differences Influence Murine Pulmonary (steel) responses as well as pulmonary infections (13). Exposure to mycotoxin-producing fungi may cause other severe effects (46). In particular, Stachybotrys chartarum (previously called Stachybotrys atra) has been associated with diverse symptoms suchasmuscleaches,headaches,cough,pulmonaryhemorrhage,

Cited by 21Publish Year 2010Author Jamie H. Rosenblum Lichtenstein, Ramon M. Molina, Thomas C. Donaghey, Chidozie J. Amuzie, James J. P pulmonary responses to stachybotrys chartarum and itsPulmonary Responses to Stachybotrys chartarum and Its pulmonary responses to stachybotrys chartarum and its

Pulmonary Responses to Stachybotrys chartarum and Its Toxins Mouse Strain Affects Clearance and Macrophage Cytotoxicity Jamie H. Rosenblum Lichtenstein,*,1 Ramon M. Molina,* Thomas C. Donaghey,* Chidozie J. Amuzie James J. Pestka, Brent A. Coull, and Joseph D. Brain* *Department of Environmental Health, Program in Molecular and(plate) Cited by 2Publish Year 2020Author Tara L. Croston, Angela R. Lemons, Mark A. Barnes, William T. Goldsmith, Marlene S. Orandle, Ajay P pulmonary responses to stachybotrys chartarum and its.Stachybotrys Harvard Catalyst Profiles Harvard Catalyst(steel) Stachybotrys "Stachybotrys" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.(plate) Cited by 313Publish Year 1998Author Michael J. Hodgson, Philip Morey, Wing-Yan Leung, Lisa Morrow, David Miller, Bruce B. Jarvis, Howard pulmonary responses to stachybotrys chartarum and itsStachybotrys Literature Review - Paradigm Change(steel) Pulmonary responses to Stachybotrys chartarum and its toxins mouse strain affects clearance and macrophage cytotoxicity. Toxicological sciences an ofcial journal of the Society of Toxicology. 2010;116:113121. Rand Thomas G., Miller J. David. Immunohistochemical and immunocytochemical

Cited by 33Publish Year 2005Author Iwona Yike, Thomas G. Rand, Dorr G. DearbornReduction of Pulmonary Toxicity of Stachybotrys chartarum pulmonary responses to stachybotrys chartarum and its

The fungus Stachybotrys chartarumhas been implicated in cases of nonspecific indoor air quality complaints in adults and in cases of pulmonary hemorrhaging in infants. The effects that have been described have been attributed to mycotoxins.(plate) Cited by 3Publish Year 2016Author J. H. Kim, L. A. Harvey, A. L. Evans, G. E. Byfield, D. A. Betancourt, T. R. DeanUpdate Pulmonary Hemorrhage/Hemosiderosis Among (steel) BackgroundCase IdentificationAssociation of Household AIPH with Water Damage and FungiEvaluation of Analysis MethodsIn December 1994 and January 1997, articles inMMWR described a cluster of 10* infants from Cleveland, Ohio, with acute idiopathic pulmonary hemorrhage, alsoreferred to as pulmonary hemosiderosis (1,2). The children resided inseven contiguous postal tracts and had had one or more hemorrhagic episodes, resultingin one death, during January 1993-December 1994. Preliminary results of a CDCcase-control study (2) indicated that hemorrhage was associated with 1) majorhousehold water damage during the See more on cdc.gov(PDF) Strain Differences Influence Murine Pulmonary pulmonary responses to stachybotrys chartarum and its(steel) When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause lung injury and inflammation. The severity of human responses to S. chartarum in both occupational and home settings pulmonary responses to stachybotrys chartarum and its(plate) Cited by 5Publish Year 2016Author Jamie H. Rosenblum Lichtenstein, Ramon M. Molina, Thomas C. Donaghey, Yi-Hsiang H. Hsu, Joel A. Math pulmonary responses to stachybotrys chartarum and itsHealth Effects of Stachybotrys Chartarum - Respiratory pulmonary responses to stachybotrys chartarum and its(steel) Rosenblum Lichtenstein JH, Molina RM, Donaghey TC, Brain JD. Strain differences influence murine pulmonary responses to Stachybotrys chartarum. American journal of respiratory cell and molecular biology. 2006;35:415 423. PMID 16690987. When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause lung injury and inflammation.

Cited by 7Publish Year 2007Author K.C. McCrae, T.G. Rand, R.A. Shaw, H.H. Mantsch, M.G. Sowa, J.A. Thliveris, J.E. ScottDozie Amuzie DVM, PhD, DACVP, DABT - Scientific Director pulmonary responses to stachybotrys chartarum and its

Pulmonary Responses to Stachybotrys chartarum and Its Toxins Mouse Strain Affects Clearance and Macrophage Cytotoxicity Toxicological Sciences Jun 2011(plate) Cited by 87Publish Year 2000Author Carol Y. Rao, Harriet A. Burge, Joseph D. BrainKilling Two Birds with One Stone Mold-induced Pulmonary pulmonary responses to stachybotrys chartarum and its(steel) In this issue of the Journal, Croston and colleagues (pp. 563576) show both pulmonary arterial remodeling and a mixed T-helper cell type 1 (Th1)/Th2 T-cell response to two different strains of the toxic mold Stachybotrys chartarum(1). Their project was designed to explore pulmonary immune responses to (plate) Cited by 91Publish Year 2000Author Charles Albert Sakakini Nagaraja Rao, Joseph David Brain, Harriet Ann BurgeJoseph Brain Harvard T.H. Chan School of Public Health(steel) Pulmonary responses to Stachybotrys chartarum and its toxins Mouse strain affects clearance and macrophage cytotoxicity. Toxicol Sci. 2010 Jul;116(1):113-21. Molina RM, Phattanarudee S, Kim J, Thompson K, Wessling-Resnick M, Maher TJ, Brain JD.

DNA fragmentation in developing lung fibroblasts exposed pulmonary responses to stachybotrys chartarum and its

May 29, 2007Stachybotrys chartarum (atra) is a toxic mold that grows on waterdamaged cellulosebased materials. Research has revealed also that inhalation of S. chartarum spores caused marked changes in respiratory epithelium, especially to developing lungs. We analyzed the epigenetic potential of S. chartarum spore toxins on developing rat lung fibroblasts using single cell gel (plate) Images of pulmonary responses to Stachybotrys Chartarum a(steel) imagesStrain differences influence murine pulmonary responses to pulmonary responses to stachybotrys chartarum and its(steel) When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause lung injury and inflammation. The severity of human responses to S. chartarum in both occupational and home settings varies widely. To explore these differences, we intratracheally instilled C3H/HeJ, BALB/c, and C57BL/6J mice with S. chartarum spores suspended in saline.(plate) Infectious Disease Epidemiology Section Office of Public pulmonary responses to stachybotrys chartarum and its(steel) demonstrated in the air of Stachybotrys chartarumcontaminated buildings Journal of Allergy and Clinical Immunology This correspondence is in response to the American Academy of Allergy, Asthma and Immunology position paper recently published in the

Inhalation of Stachybotrys chartarum Fragments Induces pulmonary responses to stachybotrys chartarum and its

Stachybotrys chartarum is a fungal contaminant within the built environment and a respiratory health concern in the United States. The objective of this study was to characterize the mechanisms influencing pulmonary immune responses to repeatedly inhaled S. chartarum.Groups of B6C3F1/N mice repeatedly inhaled viable trichothecene-producing S. chartarum conidia (strain A or strain B), heat pulmonary responses to stachybotrys chartarum and its(plate) Inhalation of Stachybotrys chartarum causes pulmonary pulmonary responses to stachybotrys chartarum and its(steel) Inhalation of Stachybotrys chartarum, a ubiquitous fungus in our living environment, has been suspected as a cause of acute idiopathic pulmonary haemorrhage in infants, but its relation to human diseases is not yet known. The aim of present study was to investigate the effect of repeated intratracheal injection of the fungus into mice, paying special attention to the pulmonary vascular system.(plate) Jamie Rosenblum Lichtenstein - Adjunct Professor - Emerson pulmonary responses to stachybotrys chartarum and its(steel) Strain differences influence murine pulmonary responses to Stachybotrys chartarum Am J Respir Cell Mol Biol. Oct 2006 When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause pulmonary responses to stachybotrys chartarum and its

Killing Two Birds with One Stone Mold-induced

Stachybotrys chartarum shift immune response from type 1 to type 2. Am J Respir Cell Mol Biol 2016;55:521531. 12. Lichtenstein JH, Molina RM, Donaghey TC, Amuzie CJ, Pestka JJ, Coull BA, et al. Pulmonary responses to Stachybotrys chartarum and its toxins mouse strain affects clearance and macrophage cytotoxicity. Toxicol Sci 2010;116:113 pulmonary responses to stachybotrys chartarum and its(plate) NIOSHTIC-2 Publications Search - 20020789 - The time pulmonary responses to stachybotrys chartarum and its(steel) Stachybotrys chartarum is a fungal species that can produce mycotoxins, specifically trichothecenes. Exposures in the indoor environment have reportedly induced neurogenic symptoms in adults and hemosiderosis in infants. However, little evidence has linked measured exposures to any fungal agent with any health outcome. We present here a study that focuses on quantitatively assessing the health ris(plate) Publications Joseph Brain Harvard T.H. Chan School of pulmonary responses to stachybotrys chartarum and its(steel) Pulmonary responses to Stachybotrys chartarum and its toxins Mouse strain affects clearance and macrophage cytotoxicity. Toxicol Sci. 2010 Jul;116(1):113-21. Molina RM, Phattanarudee S, Kim J, Thompson K, Wessling-Resnick M, Maher TJ, Brain JD.

Pulmonary Hemorrhage/Hemosiderosis Among Infants

In June 1997, a CDC scientific task force, in a review of the agency's response to the problem, advised the CDC director that concerns about the role of S. chartarum in pulmonary hemorrhage needed pulmonary responses to stachybotrys chartarum and its(plate) Pulmonary Responses to Stachybotrys chartarum and Its pulmonary responses to stachybotrys chartarum and its(steel) Inhalation of fungal spores and their mycotoxins initiates inflammatory and allergic responses as well as pulmonary infections (Hendry and Cole, 1993; Larsen et al., 1996).Inhalation of Stachybotrys chartarum has been associated with multiple symptoms, including muscle aches, headaches, cough, pulmonary hemorrhage, dermatitis, and interstitial lung disease (Cooley et al., 1998).(plate) Pulmonary Responses to Stachybotrys chartarum and Its pulmonary responses to stachybotrys chartarum and its(steel) Pulmonary Responses to Stachybotrys chartarum and Its Toxins Mouse Strain Affects Clearance and Macrophage Cytotoxicity

Repeated Mouse Lung Exposures to Stachybotrys chartarum pulmonary responses to stachybotrys chartarum and its

Stachybotrys chartarumis a mold that is most problematic in indoor environments (1). It is associated with pulmonary responses, such as asthma, pulmonary hemorrhage, inflammation, runny nose, and cough, in both humans and mice (2, 3).(plate) Special Article - Stachybotrys chartarum(steel) May 08, 2020The toxic effects from mycotoxins produced by Stachybotrys chartarum pulmonary responses to stachybotrys chartarum and its nor the weak association between Stachybotrys and pulmonary pulmonary responses to stachybotrys chartarum and its of interest related to your comments and responses.(plate) Stachybotrys Chartarum Mold-Help - The world's pulmonary responses to stachybotrys chartarum and its(steel) Recognizing StachybotrysSymptoms Reported with ExposureToxin ProductionCharacteristicsFirst ReportsHistorical Health EffectsPrevention and HelpImportant FindingsConclusions and RecommendationsAdditional Reading on StachybotrysStachybotrys grows on material with a high cellulose content, such as hay, straw, wicker, and wood chips, as well as building materials such as ceiling tile, drywall, paper vapor barriers, wallpaper, insulation backing, cardboard boxes, paper files, fiberboard, the paper covering of gypsum wallboard, particleboard, jute, dust, and wood when these items become water damaged. Stachybotrys also loves metal, where it turns into rust. This mold can grow in the Arctic and in temperatures beyond. Black mold knows no temSee more on mold-helpStachybotrys - Allergy, Health Symptoms & Treatment (steel) Stachybotrys mold is a type of mold that is often found inside the house. Famously referred to as black mold, it is sticky to the touch and is greenish-black colour. It is also popularly known as toxic mold due to its association with pulmonary hemosiderosis in infants in

Stachybotrys chartarum-Induced Hypersensitivity pulmonary responses to stachybotrys chartarum and its

Dec 01, 2011Stachybotrys chartarum (SC) is a dimorphic fungus implicated in a number of respiratory illnesses, including HP. Here, we have developed a murine model of SC-induced HP that reproduces pathology observed in human HP and hypothesized that toll receptor-like 9 (TLR9)-mediated dendritic cell responses are required for the generation of pulmonary responses to stachybotrys chartarum and its(plate) Strain Differences Influence Murine Pulmonary Responses to pulmonary responses to stachybotrys chartarum and its(steel) Oct 01, 2006In particular, Stachybotrys chartarum (previously called Stachybotrys atra) has been associated with diverse symptoms such as muscle aches, headaches, cough, pulmonary hemorrhage, dermatitis, and interstitial lung disease after inhalation exposures (7 10).(plate) Strain Differences Influence Murine Pulmonary Responses to pulmonary responses to stachybotrys chartarum and its(steel) When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause lung injury and inflammation. The severity of human responses to S. chartarum in both occupational and home settings varies widely. To explore these differences, we intratracheally instilled C3H/HeJ, BALB/c, and C57BL/6J mice with S. chartarum spores suspended in saline.

The time course of responses to intratracheally instilled pulmonary responses to stachybotrys chartarum and its

We have demonstrated that a single, acute pulmonary exposure to a large quantity of Stachybotrys chartarum spores by intratracheal instillation causes severe injury detectable by bronchoalveolar lavage. The primary effect appears to be cytotoxicity and inflammation with hemorrhage.(plate) Title Adjunct Professor at Emerson Location Boston, MassachusettsConnections 434Jamie Lichtenstein Emerson College(steel) Her research focuses on pulmonary and cellular inflammatory responses to the toxic mold Stachybotrys chartarum and its mycotoxins. Lichtenstein teaches SC210 Human Health and Disease, SC211 Food and Nutrition, SC212 Evolution of Human Nature, and SC216 DNA and Society.(plate) Title Scientific Director at Janssen Location Greater Philadelphia500+ connectionsGlobal Indoor Health Network - Research Papers (P-S)(steel) Strain Differences Influence Murine Pulmonary Responses to Stachybotrys chartarum (2006) Structure-function Relationship of T-2 Toxin and its Metabolites in Inducing Thymic Apoptosis in Vivo in Mice (1998) Studies on the "Kerosene Fungus" Cladosporium Resinae (Lindau) DeVries Part I. The Problem of Microbial Contamination of Aviation Fuels (1971)

Stachybotrys chartarumis a mold that is most problematic in indoor environments (1). It is associated with pulmonary responses, such as asthma, pulmonary hemorrhage, inflammation, runny nose, and cough, in both humans and mice (2, 3).Cited by: 5Publish Year: 2016Repeated Mouse Lung Exposures to Stachybotrys chartarum pulmonary responses to stachybotrys chartarum and its

Was this helpful?People also askIs Stachybotrys mold harmful?Is Stachybotrys mold harmful?Worryingly, some species of Stachybotrys produce mycotoxins which can be harmful to human beings if inhaled or ingested. Depending on factors such as temperature, humidity, and the nature of the surface its growing on, the Stachybotrys mold may or may not produce mycotoxins.Stachybotrys - Allergy, Health Symptoms & Treatment Mold pulmonary responses to stachybotrys chartarum and its

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